Antibiotic Formulary

​​​​Acute Dental Abscess 

Causative organisms: Streptococcus milleri, anaerobes

First Line Second Line  ​​​Allergy status (Confirm allergy status prior to choosing antimicrobial regime) ​ No penicillin allergy ​​ Penicillin allergy​ Antimicrobial   Check for interactions     Amoxicillin        Clarithromycin  Dose  Amoxicillin 500mg every 8 hours   If evidence of spreading infection add in metronidazole 400mg every 8 hours Clarithromycin 500mg every 12 hours   If evidence of spreading infection add in metronidazole 400mg every 8 hours​ Route  PO  PO  Duration   7 days

Additional Information

• Clarithromycin is a potent enzyme inhibitor and interacts with many drugs.  Please check the BNF for information on drug interactions and discuss with pharmacy​.​​